Article
Serotonin transporter polymorphism alters citalopram effects on human pain responses to physical pain.
NeuroImage - 15 Jul 2016
Ma Yina, Wang Chenbo, Luo Siyang, Li Bingfeng, Wager Tor D, Zhang Wenxia, Rao Yi, Han Shihui
Abstract excerpt
Humans exhibit substantial inter-individual differences in pain perception, which contributes to variability in analgesic efficacy. Individual differences in pain sensitivity have been linked with variation in the serotonin transporter gene (5-HTTLPR), and selective serotonin reuptake inhibitors (SSRIs) such as citalopram have been increasingly used as treatments for multiple pain conditions. We combined...
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