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Article

The association between selected genetic variants and individual differences in experimental pain.

Scandinavian journal of pain - 27 Jan 2021

Lie Marie Udnesseter, Winsvold Bendik, Gjerstad Johannes, Matre Dagfinn, Pedersen Linda M, Heuch Ingrid, Zwart John-Anker, Nilsen Kristian Bernhard

Abstract excerpt

OBJECTIVES: The underlying mechanisms for individual differences in experimental pain are not fully understood, but genetic susceptibility is hypothesized to explain some of these differences. In the present study we focus on three genetic variants important for modulating experimental pain related to serotonin (SLC6A4 5-HTTLPR/rs25531 A>G), catecholamine (COMT rs4680 Val158Met) and opioid (OPRM1 rs1799971 A118G)...

Topics

Catechol O-Methyltransferase
Humans
Individuality

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pain

Pain Threshold

Polymorphism, Single Nucleotide

Receptors, Opioid, mu

Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 33108341
DOI: 10.1515/sjpain-2020-0091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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