Article
[The Mutations on embA, embB and embC Gene Region in Ethambutol-Resistant and Susceptible Clinical Mycobacterium tuberculosis Complex Isolates].
Mikrobiyoloji bulteni - 1 Jan 2023
Yaşar Nurbanu, Tezcan Ülger Seda, Ülger Mahmut, Arslantürk Ahmet, Aslan Gönül, Köksal Fatih
Abstract excerpt
Ethambutol (EMB) is one of the first-line drugs used in the standard combination therapy for tuberculosis (TB) caused by Mycobacterium tuberculosis complex (MTC), and resistance to drugs that play a key role in treatment is increasing worldwide. Mutations in the embCAB operon that have been confirmed to be associated with resistance are responsible for EMB resistance. In this study, it was aimed to determine the...
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