Article
Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.
Journal of sleep research - 1 Dec 2016
Spada Janek, Scholz Markus, Kirsten Holger, Hensch Tilman, Horn Katrin, Jawinski Philippe, Ulke Christine, Burkhardt Ralph, Wirkner Kerstin, Loeffler Markus, Hegerl Ulrich, Sander Christian
Abstract excerpt
The genetic basis of sleep is still poorly understood. Despite the moderate to high heritability of sleep-related phenotypes, known genetic variants explain only a small proportion of the phenotypical variance. However, most previous studies were based solely upon self-report measures. The present study aimed to conduct the first genome-wide association (GWA) of actigraphic sleep phenotypes. The analyses included...
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