Article

The impact of Mendelian sleep and circadian genetic variants in a population setting

2022-01-05

Abstract excerpt

<h4>ABSTRACT</h4> Rare variants in ten genes have been reported to cause Mendelian sleep conditions characterised by extreme sleep duration or timing. These include familial natural short sleep ( ADRB1, DEC2/BHLHE41, GRM1 and NPSR1 ), advanced sleep phase ( PER2, PER3, CRY2, CSNK1D and TIMELESS ) and delayed sleep phase ( CRY1 ). The association of variants of these genes with extreme sleep conditions were usually...

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Literature Corpus work: 5cd572ff-15bd-5042-b4df-6ad69e832521
DOI: 10.1101/2022.01.04.21268199

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