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Article

Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration.

Nature communications - 28 Sept 2023

Austin-Zimmerman Isabelle, Levey Daniel F, Giannakopoulou Olga, Deak Joseph D, Galimberti Marco, Adhikari Keyrun, Zhou Hang, Denaxas Spiros, Irizar Haritz, Kuchenbaecker Karoline, McQuillin Andrew, Concato John, Buysse Daniel J, Gaziano J Michael, Gottlieb Daniel J, Polimanti Renato, Stein Murray B, Bramon Elvira, Gelernter Joel

Abstract excerpt

Sleep duration has been linked to a wide range of negative health outcomes and to reduced life expectancy. We present genome-wide association studies of short ( ≤ 5 h) and long ( ≥ 10 h) sleep duration in adults of European (N = 445,966), African (N = 27,785), East Asian (N = 3141), and admixed-American (N = 16,250) ancestry from UK Biobank and the Million Veteran Programme. In a cross-population meta-analysis,...

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PMID: 37770476
DOI: 10.1038/s41467-023-41249-y
PMCID: PMC10539313

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