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Article

Ultrafine mapping of Dyscalc1 to an 80-kb chromosomal segment on chromosome 7 in mice susceptible for dystrophic calcification.

Physiological genomics - 17 Jan 2007

Aherrahrou Zouhair, Doehring Lars C, Kaczmarek Piotr M, Liptau Henrike, Ehlers Eva-Maria, Pomarino Andrea, Wrobel Sandra, Götz Anika, Mayer Bjoern, Erdmann Jeanette, Schunkert Heribert

Abstract excerpt

In mice, dystrophic cardiovascular calcification (DCC) is controlled by a major locus on proximal mouse chromosome 7 named Dyscalc1. Here we present a strategy that combines in silico analysis, expression analysis, and extensive sequencing for ultrafine mapping of the Dyscalc1 locus. We subjected 15 laboratory mouse strains to freeze-thaw injury of the heart, and association with respective genotypes allowed...

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PMID: 16926270
DOI: 10.1152/physiolgenomics.00133.2006

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DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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