Article
A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background.
Genomics - 1 Sept 2005
Davis Richard C, Schadt Eric E, Smith Desmond J, Hsieh Elena W Y, Cervino Alessandra C L, van Nas Atila, Rosales Melenie, Doss Sudheer, Meng Haijin, Allayee Hooman, Lusis Aldons J
Abstract excerpt
In the analysis of complex traits, congenic strains are powerful tools because they allow characterization of a single locus in the absence of genetic variation throughout the remainder of the genome. Here, we report the construction and initial characterization of a genome-wide panel of congenic strains derived from the donor strain DBA/2J on the background strain C57BL/6J. For many strains, we have carried out...
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