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Article

Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation.

Molecular cancer - 30 Jan 2017

Lee Su Yeon, Jeong Eui Kyong, Ju Min Kyung, Jeon Hyun Min, Kim Min Young, Kim Cho Hee, Park Hye Gyeong, Han Song Iy, Kang Ho Sung

Abstract excerpt

Radiation therapy is one of the major tools of cancer treatment, and is widely used for a variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or indirectly via the generation of reactive oxygen species (ROS), thereby destroying cancer cells. However, ionizing radiation (IR) paradoxically promotes metastasis and invasion of cancer cells by inducing the epithelial-mesenchymal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28137309
DOI: 10.1186/s12943-016-0577-4
PMCID: PMC5282724

Genes

EGFR
STAT3
ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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