Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation analysis of metastatic melanomas in the central nervous system: results of a panel of 5 genes in 48 cases.

Clinical neuropathology - 1 Jan 2000

Gamsizkan Mehmet, Yilmaz Ismail, Simsek Hasan Aktug, Onguru Onder, Griffin Ann, Tihan Tarik

Abstract excerpt

Melanocytic lesions in the central nervous system (CNS) may be primary to the site but are more commonly metastases from cutaneous primaries. In fact, melanomas are one of the most common malignancies that can metastasize to the brain, and some patients may not have a diagnosis of melanoma prior to the discovery of the CNS lesion. In such cases, identifying the primary site may be challenging. We reviewed the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Brain Neoplasms

Share to DNA Mutational Analysis

Share to Melanoma

Share to Polymerase Chain Reaction

Share to Young Adult

Source

Identifiers

PMID: 27117140
DOI: 10.5414/NP300941

Genes

GNAQ
BRAF
GNA11
NRAS
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation analysis of metastatic melanomas in the central nervous system: results of a panel of 5 genes in 48 cases.PMID 27117140Read ↗

Targeted next generation sequencing reveals unique mutation profile of primary melanocytic tumors of the central nervous system.Semantic proximity Read ↗

Primary melanocytic tumors of the central nervous system: a review with focus on molecular aspects.Semantic proximity Read ↗

Activating mutations of the GNAQ gene: a frequent event in primary melanocytic neoplasms of the central nervous system.Semantic proximity Read ↗

Genomic analysis reveals low tumor mutation burden which may be associated with GNAQ/11 alteration in a series of primary leptomeningeal melanomas.Semantic proximity Read ↗

Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma.Semantic proximity Read ↗

Intraventricular melanocytoma diagnosis confirmed by gene mutation profile.Semantic proximity Read ↗

Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling.Semantic proximity Read ↗

NRASQ61K mutated diffuse leptomeningeal melanomatosis in an adult patient with a brief review of the so-called "forme fruste" of neurocutaneous melanosis.Semantic proximity Read ↗

Utility of next-generation sequencing in the diagnosis of metastatic melanoma: A case report.Semantic proximity Read ↗

High throughput mass spectrometry-based mutation profiling of primary uveal melanoma.Semantic proximity Read ↗

The Prognostic Value of BRAF, C-KIT, and NRAS Mutations in Melanoma Patients With Brain Metastases.Semantic proximity Read ↗

Primary leptomeningeal melanoma: the prognostic significance of its genetic signature and embryological origin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.