Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of linker length between variable domains of single chain variable fragment antibody against daidzin on its reactivity

27 Apr 2016

Abstract excerpt

The peptide linker between variable domains of heavy (VH) and light (VL) chains is one of important factors that influence the characteristics of scFv, including binding activity and specificity against target antigen. The scFvs against daidzin (DZ-scFvs) with different linker lengths were constructed in the format of VH-(GGGGS)n-VL (n = 1, 3, 5, and 7). They were expressed in the hemolymph of silkworm larvae...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to Transgenic Plants and Applications
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27116996
DOI: 10.1080/09168451.2016.1156482

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of linker length between variable domains of single chain variable fragment antibody against daidzin on its reactivityPMID 27116996Read ↗

Effect of non-repetitive linker on in vitro and in vivo properties of an anti-VEGF scFvSemantic proximity Read ↗

Single-chain fragment variable produced by phage display technology: Construction, selection, mutation, expression, and recent applications in food safety.Semantic proximity Read ↗

Anti-idiotypic single-chain variable fragment antibody partially mimic the functionally spatial structure of Cry2Aa toxin.Semantic proximity Read ↗

Generation and Evaluation of Chicken IgY-scFv for the Purposes of CPV Diagnosis and TherapySemantic proximity Read ↗

Characterization of scFv-Ig Constructs Generated from the Anti-CD20 mAb 1F5 Using Linker Peptides of Varying LengthsSemantic proximity Read ↗

Linkers: a synergistic way for chimeric proteinsSemantic proximity Read ↗

Selection of beet necrotic yellow vein virus specific single-chain Fv antibodies from a semi-synthetic combinatorial antibody librarySemantic proximity Read ↗

Development of an inhibiting antibody against equine interleukin 5 to treat insect bite hypersensitivity of horsesSemantic proximity Read ↗

The Gly-Gly linker region of the insect cytokine growth-blocking peptide is essential for activity.Semantic proximity Read ↗

[Characterization of anti-mouse prion peptide single chain Fv antibody by phage display].Semantic proximity Read ↗

Isolation and characterisation of deoxynivalenol affinity binders from a phage display library based on single-domain camelid heavy chain antibodies (VHHs)Semantic proximity Read ↗

Efficient production of a functional single-chain antidigoxin antibody via an engineered Bacillus subtilis expression-secretion system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.