Article
[Characterization of anti-mouse prion peptide single chain Fv antibody by phage display].
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences - 1 Jan 2009
Hachisuka Akiko, Koyano Satoru, Kikuchi Yutaka, Nakajima Osamu, Aosasa Masayoshi, Matsuda Haruo, Sawada Jun-ichi, Teshima Reiko
Abstract excerpt
Antibodies can distinguish not only differences in amino acid sequences (primary structure), but also differences in three-dimensional structure and thus may be useful for detecting the conversion of prion proteins, especially in vivo. For diagnosis, we prepared chicken single chain variable frag...
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