Article
SEPT14 Is Associated with a Reduced Risk for Parkinson's Disease and Expressed in Human Brain.
Journal of molecular neuroscience : MN - 1 Jul 2016
Rozenkrantz Liron, Gan-Or Ziv, Gana-Weisz Mali, Mirelman Anat, Giladi Nir, Bar-Shira Anat, Orr-Urtreger Avi
Abstract excerpt
Genes involved in cytoskeletal stability and trafficking, such as MAPT and SNCA, are important risk factors for Parkinson's disease (PD). Two members of the cytoskeletal Septin family, SEPT4 and SEPT5, were implicated in PD pathobiology. We aimed to determine whether Septin genes are associated with Parkinson's disease. To this end, six SNPs located in four different Septin loci were analyzed in 720 PD patients...
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