Article
Identification of SEPP1 polymorphisms is not a genetic risk factor for preeclampsia in Chinese Han women: A clinical trial and experimental study.
Medicine - 1 Jul 2017
Wu Hong, Jia Xuewen, Zhao Hong, Huang Youmin, Liu Chang, Huang Zuzhou, Li Shunjun, Wang Jingli
Abstract excerpt
BACKGROUND: SEPP1 encodes selenoprotein P, which involved in oxidative stress and plays an important role in the development of preeclampsia (PE). The aim of this study was to investigate the association between PE and genetic variants of SEPP1 in Chinese Han women. METHODS: In all, 2434 unrelated pregnant women were recruited, including 1034 PE cases and 1400 normal pregnant controls. TaqMan allelic...
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