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Article

Susceptibility loci for preeclampsia on chromosomes 2p25 and 9p13 in Finnish families.

American journal of human genetics - 1 Jan 2003

Laivuori Hannele, Lahermo Päivi, Ollikainen Vesa, Widen Elisabeth, Häivä-Mällinen Leena, Sundström Helena, Laitinen Tarja, Kaaja Risto, Ylikorkala Olavi, Kere Juha

Abstract excerpt

Preeclampsia is a common, pregnancy-specific disorder characterized by reduced placental perfusion, endothelial dysfunction, elevated blood pressure, and proteinuria. The pathogenesis of this heterogeneous disorder is incompletely understood, but it has a familial component, which suggests that one or more common alleles may act as susceptibility genes. We hypothesized that, in a founder population, the genetic...

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PMID: 12474145
DOI: 10.1086/345311
PMCID: PMC378622

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NPL

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Susceptibility loci for preeclampsia on chromosomes 2p25 and 9p13 in Finnish families.PMID 12474145Read ↗

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Protective Low-Frequency Variants for Preeclampsia in the Fms Related Tyrosine Kinase 1 Gene in the Finnish Population.Semantic proximity Read ↗

A genome-wide scan reveals a maternal susceptibility locus for pre-eclampsia on chromosome 2p13.Semantic proximity Read ↗

The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.Semantic proximity Read ↗

Microsatellite marker association at chromosome region 2p13 in Finnish patients with preeclampsia and obstetric cholestasis suggests a common risk locus.Semantic proximity Read ↗

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A genome scan in families from Australia and New Zealand confirms the presence of a maternal susceptibility locus for pre-eclampsia, on chromosome 2.Semantic proximity Read ↗

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