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Association of the polymorphisms in the gene encoding thyroglobulin with the development and prognosis of autoimmune thyroid disease.

Autoimmunity - 1 Sept 2017

Mizuma Tomoyo, Watanabe Mikio, Inoue Naoya, Arakawa Yuya, Tomari Saki, Hidaka Yoh, Iwatani Yoshinori

Abstract excerpt

Graves' disease (GD) and Hashimoto's disease (HD) are autoimmune thyroid diseases (AITDs), and the prognosis of AITDs is different for each patient. We examined the association of polymorphisms in the Thyroglobulin (TG) gene with the pathogenesis of AITD. We genotyped TG rs180195G/A, rs853326G/A, rs2076740C/T, rs2703013G/T, rs2958692C/T and rs733735A/G polymorphisms in 137 HD patients, 131 GD patients and 89...

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Autoantibodies
Case-Control Studies
Gene Expression
Graves Disease
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hashimoto Disease

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PMID: 28675712
DOI: 10.1080/08916934.2017.1344971

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