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Article

Common NOD2/CARD15 and TLR4 Polymorphisms Are Associated with Crohn's Disease Phenotypes in Southeastern Brazilians.

Digestive diseases and sciences - 1 Sept 2016

Tolentino Yolanda F M, Elia Paula Peruzzi, Fogaça Homero Soares, Carneiro Antonio José V, Zaltman Cyrla, Moura-Neto Rodrigo, Luiz Ronir Raggio, Carvalho Maria da Gloria C, de Souza Heitor S

Abstract excerpt

AIM: To investigate whether variants in NOD2/CARD15 and TLR4 are associated with CD and ulcerative colitis (UC) in a genetically admixed population of Rio de Janeiro, where IBD has continued to rise. METHODS: We recruited 67 consecutive patients with CD, 61 patients with UC, and 86 healthy and ethnically matched individuals as controls. DNA was extracted from buccal brush samples and genotyped by PCR with...

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Source

Identifiers

PMID: 27107867
DOI: 10.1007/s10620-016-4172-8

Genes

NOD2
TLR4
TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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