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Intestinal Alkaline Phosphatase Regulates Tight Junction Protein Levels

19 Dec 2015

Abstract excerpt

BACKGROUND: Intestinal alkaline phosphatase (IAP) plays a pivotal role in maintaining gut health and well-being. Oral supplementation with IAP in mice improves gut barrier function and prevents luminal proinflammatory factors from gaining access to the circulation. In this study, we sought to explore the relationship between IAP and tight junction protein (TJP) expression and function. STUDY DESIGN: The effect of...

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PMID: 27106638
DOI: 10.1016/j.jamcollsurg.2015.12.006

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