Article
Pathway paradigms revealed from the genetics of inflammatory bowel disease.
Nature - 1 Feb 2020
Graham Daniel B, Xavier Ramnik J
Abstract excerpt
Inflammatory bowel disease (IBD) is a complex genetic disease that is instigated and amplified by the confluence of multiple genetic and environmental variables that perturb the immune-microbiome axis. The challenge of dissecting pathological mechanisms underlying IBD has led to the development of transformative approaches in human genetics and functional genomics. Here we describe IBD as a model disease in the...
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