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Article

The association between the NAT2 genetic polymorphisms and risk of DILI during anti-TB treatment: a systematic review and meta-analysis.

British journal of clinical pharmacology - 1 Dec 2018

Zhang Min, Wang Shuqiang, Wilffert Bob, Tong Rongsheng, van Soolingen Dick, van den Hof Susan, Alffenaar Jan-Willem

Abstract excerpt

AIMS: The aim of this study is to evaluate the potential association between N-acetyltransferase type 2 (NAT2) polymorphisms and drug-induced liver injury during anti-TB treatment (AT-DILI). METHODS: We conducted a systematic review and performed a meta-analysis to clarify the role of NAT2 polymorphism in AT-DILI. PubMed, Medline and EMBASE databases were searched for studies published in English to December 31,...

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Share to Antitubercular Agents
Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemical and Drug Induced Liver Injury

Share to NAT2 gene

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Genetic

Source

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Identifiers

PMID: 30047605
DOI: 10.1111/bcp.13722
PMCID: PMC6256008

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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