Article
Enhanced Megakaryopoiesis and Platelet Activity in Hypercholesterolemic, B6-Ldlr-/-, Cdkn2a-Deficient Mice.
Circulation. Cardiovascular genetics - 1 Jun 2016
Wang Wei, Oh Seon, Koester Mark, Abramowicz Sandra, Wang Nan, Tall Alan R, Welch Carrie L
Abstract excerpt
BACKGROUND: Genome-wide association studies for coronary artery disease/myocardial infarction revealed a 58 kb risk locus on 9p21.3. Refined genetic analyses revealed unique haplotype blocks conferring susceptibility to atherosclerosis per se versus risk for acute complications in the presence of underlying coronary artery disease. The cell proliferation inhibitor locus, CDKN2A, maps just upstream of the...
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