Article
Simultaneous SNP identification and assessment of allele-specific bias from ChIP-seq data.
BMC genetics - 5 Sept 2012
Ni Yunyun, Hall Amelia Weber, Battenhouse Anna, Iyer Vishwanath R
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) have been associated with many aspects of human development and disease, and many non-coding SNPs associated with disease risk are presumed to affect gene regulation. We have previously shown that SNPs within transcription factor binding sites can affect transcription factor binding in an allele-specific and heritable manner. However, such analysis has relied on...
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