Article
Determinants of altered intracellular endocrine-immune interplay in Bosnian war refugees suffering from PTSD.
Biological psychology - 1 Jul 2016
Pitts Kenneth P, Joksimovic Ljiljana, Steudte-Schmiedgen Susann, Rohleder Nicolas, Wolf Jutta M
Abstract excerpt
Posttraumatic Stress Disorder (PTSD) has been repeatedly linked to changes in glucocorticoid (GC) sensitivity. To increase our understanding of this phenomenon and its potential relevance for PTSD development and treatment, the current study investigates the interplay between two key moderators, glucocorticoid receptor (GRα) and GR co-chaperone FKBP5, and their relation to GC sensitivity. A GC sensitivity assay...
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