Article
Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: a prospective study.
Biological psychiatry - 15 Feb 2012
van Zuiden Mirjam, Geuze Elbert, Willemen Hanneke L D M, Vermetten Eric, Maas Mirjam, Amarouchi Karima, Kavelaars Annemieke, Heijnen Cobi J
Abstract excerpt
BACKGROUND: Biological correlates of posttraumatic stress disorder (PTSD) have mostly been studied using cross-sectional or posttrauma prospective designs. Therefore, it remains largely unknown whether previously observed biological correlates of PTSD precede trauma exposure. We investigated whether glucocorticoid receptor (GR) pathway components assessed in leukocytes before military deployment represent...
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