Article
Genetic markers for PTSD risk and resilience among survivors of the World Trade Center attacks.
Disease markers - 1 Jan 2011
Sarapas Casey, Cai Guiqing, Bierer Linda M, Golier Julia A, Galea Sandro, Ising Marcus, Rein Theo, Schmeidler James, Müller-Myhsok Bertram, Uhr Manfred, Holsboer Florian, Buxbaum Joseph D, Yehuda Rachel
Abstract excerpt
We have previously reported the differential expression of 17 probe sets in survivors of the 9/11 attacks with current posttraumatic stress disorder (PTSD) compared to similarly exposed survivors with no lifetime PTSD. The current study presents an expanded analysis of these subjects, including genotype at FKBP5, a modulator of glucocorticoid receptor (GR) sensitivity. It includes data from additional subjects...
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