Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development

21 Aug 2019

Abstract excerpt

Post-traumatic stress disorder (PTSD) is a condition of stress reactivity, whose clinical manifestations are evident when patients are triggered following exposure to a traumatic event. While baseline differences in gene expression of glucocorticoid signaling and inflammatory cytokines in peripheral blood mononuclear cells (PBMCs) have been associated with PTSD, these alterations do not fully recapitulate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Stress Responses and Cortisol
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31434874
DOI: 10.1038/s41398-019-0539-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker developmentPMID 31434874Read ↗

Dynamic Gene Expression Signatures Predict Psychotherapy Response in PTSDSemantic proximity Read ↗

Analysis of Post-traumatic Stress Disorder Gene Expression Profiles in a Prospective, Community-based CohortSemantic proximity Read ↗

Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neuronsSemantic proximity Read ↗

Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies.Semantic proximity Read ↗

Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neuronsSemantic proximity Read ↗

Predicting PTSD: pre-existing vulnerabilities in glucocorticoid-signaling and implications for preventive interventions.Semantic proximity Read ↗

An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress.Semantic proximity Read ↗

PTSD blood transcriptome mega-analysis: Shared inflammatory pathways across biological sex and modes of traumasSemantic proximity Read ↗

Genetic markers for PTSD risk and resilience among survivors of the World Trade Center attacks.Semantic proximity Read ↗

Altered gene expression and PTSD symptom dimensions in World Trade Center respondersSemantic proximity Read ↗

Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorderSemantic proximity Read ↗

Glucocorticoid receptor pathway components predict posttraumatic stress disorder symptom development: a prospective study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.