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Article

Identification and modification of amyloid-independent phenotypes of APOE4 mice.

Experimental neurology - 1 Jun 2016

DiBattista Amanda M, Dumanis Sonya B, Newman Joshua, Rebeck G William

Abstract excerpt

BACKGROUND: Over 70 million Americans inherit the strongest genetic risk factor for Alzheimer's disease (AD), apolipoprotein E4 (APOE4), but have no course for reducing their risk. The association of non-steroidal anti-inflammatory drug (NSAID) use with reduced risk of AD for APOE4-carriers suggests that NSAIDs may be useful in AD prevention. METHODS: We identified phenotypes associated with APOE4 in APOE...

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Source

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Identifiers

PMID: 27085394
DOI: 10.1016/j.expneurol.2016.04.014
PMCID: PMC4860139

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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