Article
UNDR ROVER - a fast and accurate variant caller for targeted DNA sequencing.
BMC bioinformatics - 16 Apr 2016
Park Daniel J, Li Roger, Lau Edmund, Georgeson Peter, Nguyen-Dumont Tú, Pope Bernard J
Abstract excerpt
BACKGROUND: Previously, we described ROVER, a DNA variant caller which identifies genetic variants from PCR-targeted massively parallel sequencing (MPS) datasets generated by the Hi-Plex protocol. ROVER permits stringent filtering of sequencing chemistry-induced errors by requiring reported variants to appear in both reads of overlapping pairs above certain thresholds of occurrence. ROVER was developed in tandem...
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