Article
Impact of polymorphisms in the HCP5 and HLA-C, and ZNRD1 genes on HIV viral load.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2016
Thørner Lise Wegner, Erikstrup Christian, Harritshøj Lene Holm, Larsen Margit Hørup, Kronborg Gitte, Pedersen Court, Larsen Carsten Schade, Pedersen Gitte, Gerstoft Jan, Obel Niels, Ullum Henrik
Abstract excerpt
AIMS: Single nucleotide polymorphisms (SNPs) in the human leucocyte antigen (HLA) complex P5 (HCP5), HLA-C, and near the zinc ribbon domain containing 1 (ZNRD1) have been shown to influence viral load (VL) set point in HIV-infected individuals with a known seroconversion onset. We aimed to determine the influence of HCP5 rs2395029, HLA-C rs9264942, and ZNRD1 rs3869068 on VL in antiretroviral-naïve individuals and...
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