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Article

Multiancestry Genome-Wide Association Study Identifies Variants in a Zinc Finger Gene Cluster as Novel Regulators of HIV Control.

The Journal of infectious diseases - 29 Apr 2026

Awada Abraham, Tough Riley H, Fellay Jacques, McLaren Paul J

Abstract excerpt

BACKGROUND: Human immunodeficiency virus 1 (HIV-1) remains a global health challenge, emphasizing the need to identify new host factors that influence pathogenesis to serve as drug targets. Identifying genetic determinants of HIV-1 control across diverse populations remains a top priority. METHODS: We conducted a multiancestry genome-wide association study (GWAS) of HIV-1 set-point viral load (spVL) leveraging...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41640362
DOI: 10.1093/infdis/jiag072

Genes

ZNF586

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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