Genetic Variant rs10757278 on Chromosome 9p21 Contributes to Myocardial Infarction Susceptibility.

doi:10.3390/ijms160511678

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Article

Genetic Variant rs10757278 on Chromosome 9p21 Contributes to Myocardial Infarction Susceptibility.

International journal of molecular sciences - 21 May 2015

Chen Guangyuan, Fu Xiuhua, Wang Guangyu, Liu Guiyou, Bai Xiuping

Abstract excerpt

Large-scale genome-wide association studies (GWAS) have revealed that rs10757278 polymorphism (or its proxy rs1333049) on chromosome 9p21 is associated with myocardial infarction (MI) susceptibility in individuals of Caucasian ancestry. Following studies in other populations investigated this association. However, some of these studies reported weak or no significant association. Here, we reevaluated this...

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PMID: 26006241
DOI: 10.3390/ijms160511678
PMCID: PMC4463723

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