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Article

SIRT3-mediated cardiac remodeling/repair following myocardial infarction

15 Sept 2018

Abstract excerpt

The recent investigations have extensively focused on the importance of sirtuins, as a highly conserved family of gene products, particularly SIRT3 in various biological and pathological processes. SIRT3, the mitochondrial NAD+-dependent deacetylase has been demonstrated to target a broad range of proteins involved in the oxidative stress, ischemia-reperfusion injury, mitochondrial metabolism homeostasis and...

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PMID: 30227330
DOI: 10.1016/j.biopha.2018.09.079

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