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Article

Structural insights and functional implications of inter-individual variability in β2-adrenergic receptor.

Scientific reports - 14 Apr 2016

Tandale Aditi, Joshi Manali, Sengupta Durba

Abstract excerpt

The human β2-adrenergic receptor (β2AR) belongs to the G protein-coupled receptor (GPCR) family and due to its central role in bronchodilation, is an important drug target. The inter-individual variability in β2AR has been implicated in disease susceptibility and differential drug response. In this work, we identified nine potentially deleterious non-synonymous single nucleotide polymorphisms (nsSNPs) using a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Adrenergic, beta-2

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Identifiers

PMID: 27075228
DOI: 10.1038/srep24379
PMCID: PMC4830965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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