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Article

Genetic Variants of Adrenoceptors.

Handbook of experimental pharmacology - 1 Jan 2024

Ahles Andrea, Engelhardt Stefan

Abstract excerpt

Adrenoceptors are class A G-protein-coupled receptors grouped into three families (α1-, α2-, and β-adrenoceptors), each one including three members. All nine corresponding adrenoceptor genes display genetic variation in their coding and adjacent non-coding genomic region. Coding variants, i.e., nucleotide exchanges within the transcribed and translated receptor sequence, may result in a difference in amino acid...

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PMID: 37578621
DOI: 10.1007/164_2023_676

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