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Article

Replenishing the cyclic-di-AMP pool: regulation of diadenylate cyclase activity in bacteria.

Current genetics - 1 Nov 2016

Pham Thi Huong, Liang Zhao-Xun, Marcellin Esteban, Turner Mark S

Abstract excerpt

Bacteria can sense environmental cues and alter their physiology accordingly through the use of signal transduction pathways involving second messenger nucleotides. One broadly conserved second messenger is cyclic-di-AMP (c-di-AMP) which regulates a range of processes including cell wall homeostasis, potassium uptake, DNA repair, fatty acid synthesis, biofilm formation and central metabolism in bacteria. The...

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PMID: 27074767
DOI: 10.1007/s00294-016-0600-8

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