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Bacterial second messenger cyclic di‐AMP in streptococci

28 Oct 2023

Abstract excerpt

Cyclic dimeric adenosine monophosphate (c-di-AMP) has been well studied in bacteria, including those of the genus Streptococcus, since the first recognition of this dinucleotide in 2008. Streptococci possess a sole diadenylate cyclase, CdaA, and distinct c-di-AMP phosphodiesterases. Interestingly, cdaA is required for viability of some streptococcal species but not all when streptococci are grown in standard...

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PMID: 37898560
DOI: 10.1111/mmi.15187

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