Article
Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus.
PLoS genetics - 1 Apr 2018
Devaux Laura, Sleiman Dona, Mazzuoli Maria-Vittoria, Gominet Myriam, Lanotte Philippe, Trieu-Cuot Patrick, Kaminski Pierre-Alexandre, Firon Arnaud
Abstract excerpt
Cyclic nucleotides are universally used as secondary messengers to control cellular physiology. Among these signalling molecules, cyclic di-adenosine monophosphate (c-di-AMP) is a specific bacterial second messenger recognized by host cells during infections and its synthesis is assumed to be necessary for bacterial growth by controlling a conserved and essential cellular function. In this study, we sought to...
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