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Article

Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection.

mBio - 12 Apr 2016

Cuypers Bart, Lecordier Laurence, Meehan Conor J, Van den Broeck Frederik, Imamura Hideo, Büscher Philippe, Dujardin Jean-Claude, Laukens Kris, Schnaufer Achim, Dewar Caroline, Lewis Michael, Balmer Oliver, Azurago Thomas, Kyei-Faried Sardick, Ohene Sally-Ann, Duah Boateng, Homiah Prince, Mensah Ebenezer Kofi, Anleah Francis, Franco Jose Ramon, Pays Etienne, Deborggraeve Stijn

Abstract excerpt

UNLABELLED: African trypanosomes, except Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, which cause human African trypanosomiasis, are lysed by the human serum protein apolipoprotein L1 (ApoL1). These two subspecies can resist human ApoL1 because they express the serum resistance proteins T. b. gambiense glycoprotein (TgsGP) and serum resistance-associated protein (SRA), respectively. Whereas in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27073096
DOI: 10.1128/mBio.02198-15
PMCID: PMC4959518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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