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Article

APOL1 expression is induced by Trypanosoma brucei gambiense infection but is not associated with differential susceptibility to sleeping sickness.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2012

Ilboudo Hamidou, Berthier David, Camara Mamadou, Camara Oumou, Kabore Jacques, Leno Mamadou, Keletigui Sow, Chantal Isabelle, Jamonneau Vincent, Belem Adrien Marie Gaston, Cuny Gérard, Bucheton Bruno

Abstract excerpt

Most African trypanosome species are sensitive to trypanolytic factors (TLFs) present in human serum. Trypanosome lysis was demonstrated to be associated with apolipoprotein L-I (APOL1). Trypanosoma brucei (T. b.) gambiense and Trypanosoma brucei rhodesiense, the two human infective trypanosome s...

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Source

Identifiers

PMID: 22691369
DOI: 10.1016/j.meegid.2012.05.010

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22691369-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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