Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

G1 and G2 variants of apolipoprotein L1 among Central African population in Trypanosoma brucei gambiense endemic rural area.

Journal of infection in developing countries - 31 Oct 2024

Mupepe Dominique M, Wameso Marie-Noelle Nl, Situakibanza Hippolyte N, Ekulu Pépé M, Makulo Jean Robert R, Kayembe Jean Marie N, Nkoy Agathe B, Mvibudulu Raggue Zm, Van den Heuvel Lambertus P, Levtchenko Elena N, Karume Kevin L, Bikoumou Victoire A, Buila Nathan B, Longo Benjamin M, Mumba Dieudonné N, M'Buyamba-Kabangu Jean René

Abstract excerpt

INTRODUCTION: Apolipoprotein L1 (APOL1) risk variants (G1, G2) are known to enhance the protective ability against human African trypanosomiasis (HAT), in addition to their role in kidney and cardiovascular disease. The effects of these variants on trypanosome infection could differ regionally owing to local adaptations of the host and pathogen. This study explored APOL1 risk variants distribution in HAT-infected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Apolipoprotein L1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross-Sectional Studies

Share to Democratic Republic of the Congo

Share to Endemic Diseases

Share to Rural Population

Share to Trypanosomiasis, African

Share to Young Adult

Source

Identifiers

PMID: 39616492
DOI: 10.3855/jidc.19495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

G1 and G2 variants of apolipoprotein L1 among Central African population in Trypanosoma brucei gambiense endemic rural area.PMID 39616492Read ↗

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis.Semantic proximity Read ↗

No evidence for association with APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populationsSemantic proximity Read ↗

No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations.Semantic proximity Read ↗

G1 is the major APOL1 risk allele for hypertension-attributed nephropathy in Central AfricaSemantic proximity Read ↗

Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection.Semantic proximity Read ↗

Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea.Semantic proximity Read ↗

SNPs in IL4 and IFNG show no protective associations with human African trypanosomiasis in the Democratic Republic of the Congo: a case-control studySemantic proximity Read ↗

Gene of the month: APOL1.Semantic proximity Read ↗

Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d’IvoireSemantic proximity Read ↗

A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations.Semantic proximity Read ↗

HLA-G 3' UTR-2 haplotype is associated with Human African trypanosomiasis susceptibility.Semantic proximity Read ↗

Identifying Darwinian selection acting on different human APOL1 variants among diverse African populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.