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Article

A comparative study of EGFR oncogenic mutations in matching tissue and plasma samples from patients with advanced non-small cell lung carcinoma.

Clinica chimica acta; international journal of clinical chemistry - 1 Jun 2016

Chai Xiaofei, Ren Pengfei, Wei Bing, Ma Jie, Mai Ling, Cram David S, Song Yongping, Guo Yongjun

Abstract excerpt

BACKGROUND: Plasma based EGFR mutation analysis is emerging as a viable alternative to tumour tissue genotyping for patients with non-small cell lung carcinoma (NSCLC). The purpose of the study was to determine the degree of concordance between EGFR genotypes derived from matching tissue and blood samples. METHODS: EGFR activating mutations L858R, exon 19 deletions, G719A/C/S and L861Q as well as resistance...

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Source

Identifiers

PMID: 27071701
DOI: 10.1016/j.cca.2016.04.003

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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