Article
Comparison of EGFR mutation status between plasma and tumor tissue in non-small cell lung cancer using the Scorpion ARMS method and the possible prognostic significance of plasma EGFR mutation status.
International journal of clinical and experimental pathology - 1 Jan 2015
Duan Huanli, Lu Junliang, Lu Tao, Gao Jie, Zhang Jing, Xu Yan, Wang Mengzhao, Wu Huanwen, Liang Zhiyong, Liu Tonghua
Abstract excerpt
BACKGROUND: The aims were to compare the consistency of epidermal growth factor receptor (EGFR) mutations in the plasma and tumor tissue of NSCLC patients, and to explore the prognostic significance of plasma EGFR mutation status in tyrosine kinase inhibitors (TKIs)-treated patients with tumor EGFR mutation. METHODS: We evaluated EGFR gene (exons 18, 19, 20 and 21) mutation status in paired plasma and tumor...
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