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Article

Risk stratification of T-cell Acute Lymphoblastic Leukemia patients based on gene expression, mutations and copy number variation.

Leukemia research - 1 Jun 2016

Mirji Gauri, Bhat Jaydeep, Kode Jyoti, Banavali Shripad, Sengar Manju, Khadke Prashant, Sait Osama, Chiplunkar Shubhada

Abstract excerpt

Gene expression, copy number variations (CNV), mutations and survival were studied to delineate TCRγδ+T-cell acute lymphoblastic leukemia (T-ALL) as a distinct subgroup from TCRαβ+T-ALL. Gene Ontology analysis showed that differential regulation of genes involved in pathways for leukemogenesis, apoptosis, cytokine-cytokine receptor interaction and antigen processing/presentation may offer a survival benefit to...

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Identifiers

PMID: 27070758
DOI: 10.1016/j.leukres.2016.03.002

Genes

BRAF
IKZF3
NOTCH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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