The Effect of Nicotine on HPA Axis Activity in Females is Modulated by the FKBP5 Genotype.

doi:10.1111/ahg.12153

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Article

The Effect of Nicotine on HPA Axis Activity in Females is Modulated by the FKBP5 Genotype.

Annals of human genetics - 1 May 2016

Koopmann Anne, Bez Jennifer, Lemenager Tagrid, Hermann Derik, Dinter Christina, Reinhard Iris, Schuster Rilana, Wiedemann Klaus, Winterer Georg, Kiefer Falk

Abstract excerpt

Tobacco smoking modulates activity in the hypothalamic-pituitary-adrenal (HPA) axis and is used to cope with stress, especially by females. The single nucleotide polymorphism (SNP) rs1360780, linked to FK506-binding protein 51 (FKBP5), has been shown to affect HPA axis functioning, and has thus been suggested as a promising candidate for indicating vulnerability to stress-related disorders. The aim of this study...

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PMID: 27062383
DOI: 10.1111/ahg.12153

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FKBP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Effect of Nicotine on HPA Axis Activity in Females is Modulated by the FKBP5 Genotype.PMID 27062383Read ↗

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