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Article

T cells are necessary for ILC2 activation in house dust mite-induced allergic airway inflammation in mice.

European journal of immunology - 1 Jun 2016

Li Bobby W S, de Bruijn Marjolein J W, Tindemans Irma, Lukkes Melanie, KleinJan Alex, Hoogsteden Henk C, Hendriks Rudi W

Abstract excerpt

Allergic asthma is a chronic inflammation of the airways mediated by an adaptive type 2 immune response. Upon allergen exposure, group 2 innate lymphoid cells (ILC2s) can be rapidly activated and represent an early innate source of IL-5 and IL-13. Here, we used a house dust mite (HDM)-driven asthma mouse model to study the induction of ILC2s in allergic airway inflammation. In BALF, lungs, and lymph nodes, ILC2...

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Identifiers

PMID: 27062360
DOI: 10.1002/eji.201546119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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