Article
Secondary CoQ10 deficiency, bioenergetics unbalance in disease and aging.
BioFactors (Oxford, England) - 1 Jul 2021
Navas Plácido, Cascajo María V, Alcázar-Fabra María, Hernández-Camacho Juan D, Sánchez-Cuesta Ana, Rodríguez Ana Belén Cortés, Ballesteros-Simarro Manuel, Arroyo-Luque Antonio, Rodríguez-Aguilera Juan Carlos, Fernández-Ayala Daniel J M, Brea-Calvo Gloria, López-Lluch Guillermo, Santos-Ocaña Carlos
Abstract excerpt
Coenzyme Q10 (CoQ10 ) deficiency is a rare disease characterized by a decreased accumulation of CoQ10 in cell membranes. Considering that CoQ10 synthesis and most of its functions are carried out in mitochondria, CoQ10 deficiency cases are usually considered a mitochondrial disease. A relevant feature of CoQ10 deficiency is that it is the only mitochondrial disease with a successful therapy available, the CoQ10...
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