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Pharmacogenetic studies in children with acute lymphoblastic leukemia in Argentina.

Leukemia & lymphoma - 1 May 2015

Aráoz Hilda Verónica, D'Aloi Karina, Foncuberta María Eugenia, Sanchez La Rosa Christian Germán, Alonso Cristina Noemí, Chertkoff Lilien, Felice Marisa

Abstract excerpt

The aim of this study was to evaluate the influence of the most common genetic variants in methylenetetrahydrofolate reductase (MTHFR), thiopurine methyltransferase (TPMT) and glutathione-S-transferases (GSTs) on the outcome of acute lymphoblastic leukemia (ALL) treatment in Argentinean children. Two hundred and eighty-six patients with ALL treated with two Berlin-Frankfurt-Münster (BFM)-based protocols were...

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Identifiers

PMID: 25110820
DOI: 10.3109/10428194.2014.951844

Genes

MTHFR
TPMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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