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Article

Glutathione S-transferase homozygous deletions and relapse in childhood acute lymphoblastic leukemia: a novel study design in a large Italian AIEOP cohort.

Pharmacogenomics - 1 Dec 2012

Franca Raffaella, Rebora Paola, Basso Giuseppe, Biondi Andrea, Cazzaniga Giovanni, Crovella Sergio, Decorti Giuliana, Fagioli Franca, Giarin Emanuela, Locatelli Franco, Poggi Vincenzo, Valsecchi Maria Grazia, Rabusin Marco

Abstract excerpt

AIM: In the AIEOP-BFM 2000 trial, 15% of pediatric patients treated according to risk-adapted polychemotherapeutic regimens relapsed. The present study aimed to investigate the influence of GST-M1 and GST-T1 deletions on clinical outcome of children with acute lymphoblastic leukemia treated accor...

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Identifiers

PMID: 23215883
DOI: 10.2217/pgs.12.169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23215883-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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