Article
Analysis of GWAS-nominated loci for lung cancer and COPD revealed a new asthma locus.
BMC pulmonary medicine - 23 Apr 2022
Madore Anne-Marie, Bossé Yohan, Margaritte-Jeannin Patricia, Vucic Emily, Lam Wan L, Bouzigon Emmanuelle, Bourbeau Jean, Laprise Catherine
Abstract excerpt
BACKGROUND: Asthma, lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are three respiratory diseases characterized by complex mechanisms underlying and genetic predispositions, with asthma having the highest calculated heritability. Despite efforts deployed in the last decades, only a small part of its heritability has been elucidated. It was hypothesized that shared genetic factors by these three...
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