Article
Analysis of the Expression and Function of Immunoglobulin-Like Transcript 4 (ILT4, LILRB2) in Dendritic Cells from Patients with Systemic Lupus Erythematosus.
Journal of immunology research - 1 Jan 2016
Guerra-de Blas Paola Del Carmen, Villaseñor-Talavera Yael Sebastián, Cruz-González Daniela de Jesús, Baranda Lourdes, Doníz-Padilla Lesly, Abud-Mendoza Carlos, González-Amaro Roberto, Monsiváis-Urenda Adriana Elizabeth
Abstract excerpt
Dendritic cells (DC) play an important role in the development and maintenance of immune tolerance. Although the inhibitory receptor ILT4/LILRB2 has been related with the tolerogenic phenotype of DC, the possible role of this receptor in the breakdown of DC tolerogenic function in systemic lupus erythematosus (SLE) has not been elucidated. In this study, we analyzed the expression and function of the inhibitory...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
